High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease
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| Veröffentlicht in: | Journal of hepatology 2017-01, Vol.66 (1), p.28-38 |
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| container_title | Journal of hepatology |
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| creator | Hedegaard, Ditte L Tully, Damien C Rowe, Ian A Reynolds, Gary M Bean, David J Hu, Ke Davis, Christopher Wilhelm, Annika Ogilvie, Colin B Power, Karen A Tarr, Alexander W Kelly, Deirdre Allen, Todd M Balfe, Peter McKeating, Jane A |
| description | Graphical abstract |
| doi_str_mv | 10.1016/j.jhep.2016.07.048 |
| format | Article |
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All rights reserved.</rights><rights>Copyright Elsevier Science Ltd. Jan 2017</rights><rights>2016 European Association for the Study of the Liver. Elsevier B.V. All rights reserved. 2016 European Association for the Study of the Liver</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c538t-e0bd027728c85c3ac3551a9717d8835ce138244f6bc7ddaba281a5fa8e562ad93</citedby><cites>FETCH-LOGICAL-c538t-e0bd027728c85c3ac3551a9717d8835ce138244f6bc7ddaba281a5fa8e562ad93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jhep.2016.07.048$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,780,784,885,3541,27915,27916,45986</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27531641$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hedegaard, Ditte L</creatorcontrib><creatorcontrib>Tully, Damien C</creatorcontrib><creatorcontrib>Rowe, Ian A</creatorcontrib><creatorcontrib>Reynolds, Gary M</creatorcontrib><creatorcontrib>Bean, David J</creatorcontrib><creatorcontrib>Hu, Ke</creatorcontrib><creatorcontrib>Davis, Christopher</creatorcontrib><creatorcontrib>Wilhelm, Annika</creatorcontrib><creatorcontrib>Ogilvie, Colin B</creatorcontrib><creatorcontrib>Power, Karen A</creatorcontrib><creatorcontrib>Tarr, Alexander W</creatorcontrib><creatorcontrib>Kelly, Deirdre</creatorcontrib><creatorcontrib>Allen, Todd M</creatorcontrib><creatorcontrib>Balfe, Peter</creatorcontrib><creatorcontrib>McKeating, Jane A</creatorcontrib><title>High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease</title><title>Journal of hepatology</title><addtitle>J Hepatol</addtitle><description>Graphical abstract</description><subject>Adaptive immunity</subject><subject>Adult</subject><subject>Antiviral Agents - pharmacology</subject><subject>Cell Compartmentation - drug effects</subject><subject>Compartmentalization</subject><subject>End Stage Liver Disease - etiology</subject><subject>End Stage Liver Disease - metabolism</subject><subject>End Stage Liver Disease - virology</subject><subject>ESLD</subject><subject>Evolution</subject><subject>Female</subject><subject>Gastroenterology and Hepatology</subject><subject>Gene expression</subject><subject>Genomes</subject><subject>Hepacivirus - drug effects</subject><subject>Hepacivirus - genetics</subject><subject>Hepacivirus - physiology</subject><subject>Hepatitis</subject><subject>Hepatitis C</subject><subject>Hepatitis C, Chronic - complications</subject><subject>Hepatitis C, Chronic - virology</subject><subject>Hepatocytes</subject><subject>High-Throughput Nucleotide Sequencing - methods</subject><subject>Humans</subject><subject>Immune response</subject><subject>Innate immunity</subject><subject>Interferon</subject><subject>Interferons - pharmacology</subject><subject>Liver - pathology</subject><subject>Liver - virology</subject><subject>Liver diseases</subject><subject>Liver transplantation</subject><subject>Male</subject><subject>Middle Aged</subject><subject>mRNA</subject><subject>Nucleotide sequence</subject><subject>Replication</subject><subject>Ribonucleases</subject><subject>Ribonucleic acid</subject><subject>RNA</subject><subject>RNA viruses</subject><subject>RNA, Viral - analysis</subject><subject>Sequence Analysis, RNA - methods</subject><subject>Spatial distribution</subject><subject>Virus Replication - drug effects</subject><subject>Viruses</subject><issn>0168-8278</issn><issn>1600-0641</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kkGLFDEQhRtR3HH1D3iQgBcvPSbpTncGZGEZXFdY8KCCt5BJqmeq7U7GJD2wgv9908466B48JVDfe1TVq6J4yeiSUda87Zf9DvZLnv9L2i5pLR8VC9ZQWtKmZo-LRS7IUvJWnhXPYuwppRVd1U-LM96KimVmUfy6xu2OBIh-mBJ6RyL8mMAZdFviO5L9dcKEkazJAcMUM3oAPUQy4IgJLEGXgi6PnCHGj3sd0ggu6QF_6t-W6Ag4W8akt5B1BwjEYgQd4XnxpMtm8OL-PS--Xr3_sr4ubz59-Li-vCmNqGQqgW4s5W3LpZHCVNpUQjC9allrpayEAVZJXtddszGttXqjuWRadFqCaLi2q-q8uDj67qfNCNbA3PSg9gFHHW6V16j-rTjcqa0_KCGEbBjPBm_uDYLP-4lJjRgNDIN24KeoWG6j5pKLOqOvH6C9n4LL4ylOJV2teMNnih8pE3yMAbpTM4yqOV3VqzldNaeraKtyuln06u8xTpI_cWbg3RGAvMwDQlDRYE4TLAYwSVmP__e_eCA3Azo0evgOtxBPczAVuaLq83xf83mxpqI1r79Vd_q8zpU</recordid><startdate>20170101</startdate><enddate>20170101</enddate><creator>Hedegaard, Ditte L</creator><creator>Tully, Damien C</creator><creator>Rowe, Ian A</creator><creator>Reynolds, Gary M</creator><creator>Bean, David J</creator><creator>Hu, Ke</creator><creator>Davis, Christopher</creator><creator>Wilhelm, Annika</creator><creator>Ogilvie, Colin B</creator><creator>Power, Karen A</creator><creator>Tarr, Alexander W</creator><creator>Kelly, Deirdre</creator><creator>Allen, Todd M</creator><creator>Balfe, Peter</creator><creator>McKeating, Jane A</creator><general>Elsevier B.V</general><general>Elsevier Science Ltd</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170101</creationdate><title>High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease</title><author>Hedegaard, Ditte L ; Tully, Damien C ; Rowe, Ian A ; Reynolds, Gary M ; Bean, David J ; Hu, Ke ; Davis, Christopher ; Wilhelm, Annika ; Ogilvie, Colin B ; Power, Karen A ; Tarr, Alexander W ; Kelly, Deirdre ; Allen, Todd M ; Balfe, Peter ; McKeating, Jane A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c538t-e0bd027728c85c3ac3551a9717d8835ce138244f6bc7ddaba281a5fa8e562ad93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adaptive immunity</topic><topic>Adult</topic><topic>Antiviral Agents - pharmacology</topic><topic>Cell Compartmentation - drug effects</topic><topic>Compartmentalization</topic><topic>End Stage Liver Disease - etiology</topic><topic>End Stage Liver Disease - metabolism</topic><topic>End Stage Liver Disease - virology</topic><topic>ESLD</topic><topic>Evolution</topic><topic>Female</topic><topic>Gastroenterology and Hepatology</topic><topic>Gene expression</topic><topic>Genomes</topic><topic>Hepacivirus - drug effects</topic><topic>Hepacivirus - genetics</topic><topic>Hepacivirus - physiology</topic><topic>Hepatitis</topic><topic>Hepatitis C</topic><topic>Hepatitis C, Chronic - complications</topic><topic>Hepatitis C, Chronic - virology</topic><topic>Hepatocytes</topic><topic>High-Throughput Nucleotide Sequencing - methods</topic><topic>Humans</topic><topic>Immune response</topic><topic>Innate immunity</topic><topic>Interferon</topic><topic>Interferons - pharmacology</topic><topic>Liver - pathology</topic><topic>Liver - virology</topic><topic>Liver diseases</topic><topic>Liver transplantation</topic><topic>Male</topic><topic>Middle Aged</topic><topic>mRNA</topic><topic>Nucleotide sequence</topic><topic>Replication</topic><topic>Ribonucleases</topic><topic>Ribonucleic acid</topic><topic>RNA</topic><topic>RNA viruses</topic><topic>RNA, Viral - 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| source | Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE |
| subjects | Adaptive immunity Adult Antiviral Agents - pharmacology Cell Compartmentation - drug effects Compartmentalization End Stage Liver Disease - etiology End Stage Liver Disease - metabolism End Stage Liver Disease - virology ESLD Evolution Female Gastroenterology and Hepatology Gene expression Genomes Hepacivirus - drug effects Hepacivirus - genetics Hepacivirus - physiology Hepatitis Hepatitis C Hepatitis C, Chronic - complications Hepatitis C, Chronic - virology Hepatocytes High-Throughput Nucleotide Sequencing - methods Humans Immune response Innate immunity Interferon Interferons - pharmacology Liver - pathology Liver - virology Liver diseases Liver transplantation Male Middle Aged mRNA Nucleotide sequence Replication Ribonucleases Ribonucleic acid RNA RNA viruses RNA, Viral - analysis Sequence Analysis, RNA - methods Spatial distribution Virus Replication - drug effects Viruses |
| title | High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease |
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