High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease

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Veröffentlicht in:	Journal of hepatology 2017-01, Vol.66 (1), p.28-38
Hauptverfasser:	Hedegaard, Ditte L, Tully, Damien C, Rowe, Ian A, Reynolds, Gary M, Bean, David J, Hu, Ke, Davis, Christopher, Wilhelm, Annika, Ogilvie, Colin B, Power, Karen A, Tarr, Alexander W, Kelly, Deirdre, Allen, Todd M, Balfe, Peter, McKeating, Jane A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Adult Antiviral Agents - pharmacology Cell Compartmentation - drug effects Compartmentalization End Stage Liver Disease - etiology End Stage Liver Disease - metabolism End Stage Liver Disease - virology ESLD Evolution Female Gastroenterology and Hepatology Gene expression Genomes Hepacivirus - drug effects Hepacivirus - genetics Hepacivirus - physiology Hepatitis Hepatitis C Hepatitis C, Chronic - complications Hepatitis C, Chronic - virology Hepatocytes High-Throughput Nucleotide Sequencing - methods Humans Immune response Innate immunity Interferon Interferons - pharmacology Liver - pathology Liver - virology Liver diseases Liver transplantation Male Middle Aged mRNA Nucleotide sequence Replication Ribonucleases Ribonucleic acid RNA RNA viruses RNA, Viral - analysis Sequence Analysis, RNA - methods Spatial distribution Virus Replication - drug effects Viruses
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