Subtypes of depressive symptoms and inflammatory biomarkers: An exploratory study on a sample of HIV-positive patients

Subtypes of depressive symptoms and inflammatory biomarkers: An exploratory study on a sample of HIV-positive patients

Highlights • Three sub-types of depressive symptoms were identified. • Somatic/cognitive-affective symptoms were associated with daily life impairment. • Severe somatic symptoms were associated with high levels of Il-6 and monocytes. • HIV viral load correlates with TNF-alpha and monocyte.

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Bibliographische Detailangaben
Veröffentlicht in:Brain, behavior, and immunity behavior, and immunity, 2016-08, Vol.56, p.105-113
Hauptverfasser: Norcini Pala, A, Steca, P, Bagrodia, R, Helpman, L, Colangeli, V, Viale, P, Wainberg, M.L
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Allergy and Immunology
Biomarkers - blood
Depression
Depression - blood
Depression - classification
Depression - immunology
Depression - physiopathology
Female
HIV
HIV Infections - blood
HIV Infections - immunology
Human immunodeficiency virus
Humans
Il-6
Inflammation - blood
Inflammation - immunology
Interleukin-6 - blood
Lentivirus
Male
Middle Aged
Monocytes
Psychiatry
Retroviridae
Somatic symptoms
Viral Load
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Beschreibung
Zusammenfassung:Highlights • Three sub-types of depressive symptoms were identified. • Somatic/cognitive-affective symptoms were associated with daily life impairment. • Severe somatic symptoms were associated with high levels of Il-6 and monocytes. • HIV viral load correlates with TNF-alpha and monocyte.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2016.02.013