Early growth faltering in post-institutionalized youth and later anthropometric and pubertal development

Background Early-life adversity that increases the risk of growth stunting is hypothesized to increase the risk of obesity and, in girls, early-onset puberty. This hypothesis was tested in children adopted from orphanages. Methods Post-institutionalized (PI) youth were compared with youth reared in...

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Veröffentlicht in:Pediatric research 2017-08, Vol.82 (2), p.278-284
Hauptverfasser: Reid, Brie M, Miller, Bradley S, Dorn, Lorah D, Desjardins, Christopher, Donzella, Bonny, Gunnar, Megan
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Sprache:eng
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Zusammenfassung:Background Early-life adversity that increases the risk of growth stunting is hypothesized to increase the risk of obesity and, in girls, early-onset puberty. This hypothesis was tested in children adopted from orphanages. Methods Post-institutionalized (PI) youth were compared with youth reared in comparable families (non-adopted; NA) on height, weight, pubertal stage, and fat mass (127 PI, 80 female; 156 NA, 85 female, aged 7–14 years). Anthropometric findings at adoption were obtained from first US clinic visits. Results Overall, 25% of PI youth were height-stunted (
ISSN:0031-3998
1530-0447
DOI:10.1038/pr.2017.35