Microbiota Disruption Induced by Early Use of Broad Spectrum Antibiotics is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation
Highlights • Intestinal microbiota play an important role in patients with allogeneic SCT • Early use of antibiotics affects intestinal microbiota composition • Early use of antibiotics influences the outcome of allogeneic SCT recipients
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| Veröffentlicht in: | Biology of blood and marrow transplantation 2017-05, Vol.23 (5), p.845-852 |
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| container_title | Biology of blood and marrow transplantation |
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| creator | Weber, Daniela Jenq, Robert R Peled, Jonathan U Taur, Ying Hiergeist, Andreas Koestler, Josef Dettmer, Katja Weber, Markus Wolff, Daniel Hahn, Joachim Pamer, Eric G Herr, Wolfgang Gessner, André Oefner, Peter J van den Brink, Marcel R.M Holler, Ernst |
| description | Highlights • Intestinal microbiota play an important role in patients with allogeneic SCT • Early use of antibiotics affects intestinal microbiota composition • Early use of antibiotics influences the outcome of allogeneic SCT recipients |
| doi_str_mv | 10.1016/j.bbmt.2017.02.006 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1083-8791 |
| ispartof | Biology of blood and marrow transplantation, 2017-05, Vol.23 (5), p.845-852 |
| issn | 1083-8791 1523-6536 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5546237 |
| source | MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Acute intestinal GVHD Adult Allogeneic stem cell transplantation Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - pharmacology Clostridium - drug effects Female Gastrointestinal Microbiome - drug effects Graft vs Host Disease - etiology Graft vs Host Disease - mortality Hematology, Oncology and Palliative Medicine Humans Infections - etiology Infections - mortality Intestinal microbiome Male Outcome Retrospective Studies Risk Factors Stem Cell Transplantation - adverse effects Stem Cell Transplantation - methods Stem Cell Transplantation - mortality Survival Analysis Time-to-Treatment Transplantation, Homologous Treatment Outcome Treatment with broad-spectrum antibiotics Young Adult |
| title | Microbiota Disruption Induced by Early Use of Broad Spectrum Antibiotics is an Independent Risk Factor of Outcome after Allogeneic Stem Cell Transplantation |
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