Cell invasion by the vertebrate stages of Plasmodium

Protozoans of the genus Plasmodium are the causative agents of malaria; they have a complex life cycle involving vertebrate and arthropod hosts and have three distinct invasive stages. Although the invasive stages probably invade cells using similar mechanisms, each stage has a different host cell s...

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Veröffentlicht in:	Trends in microbiology (Regular ed.) 1997-02, Vol.5 (2), p.52-58
Hauptverfasser:	Sinnis, Photini, Kim Lee Sim, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Binding Sites Cell Adhesion Erythrocytes - parasitology Humans Liver - parasitology Malaria - etiology Malaria - parasitology Molecular Sequence Data Plasmodium - growth & development Plasmodium - pathogenicity Plasmodium - physiology Protozoan Proteins - genetics Protozoan Proteins - physiology Vertebrates
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Beschreibung
Zusammenfassung:	Protozoans of the genus Plasmodium are the causative agents of malaria; they have a complex life cycle involving vertebrate and arthropod hosts and have three distinct invasive stages. Although the invasive stages probably invade cells using similar mechanisms, each stage has a different host cell specificity and utilizes different receptors to enter cells.
ISSN:	0966-842X 1878-4380
DOI:	10.1016/S0966-842X(97)84657-4