Serum Potassium, Mortality, and Kidney Outcomes in the Atherosclerosis Risk in Communities Study

Abstract Objectives To investigate the association between serum potassium, mortality, and kidney outcomes in the general population and whether potassium-altering medications modify these associations. Patients and Methods We studied 15,539 adults in the Atherosclerosis Risk in Communities Study. C...

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Veröffentlicht in:	Mayo Clinic proceedings 2016-10, Vol.91 (10), p.1403-1412
Hauptverfasser:	Chen, Yan, MHS, Chang, Alex R., MD, MS, McAdams DeMarco, Mara A., PhD, Inker, Lesley A., MD, MS, Matsushita, Kunihiro, MD, PhD, Ballew, Shoshana H., PhD, Coresh, Josef, MD, PhD, Grams, Morgan E., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Atherosclerosis Chronic kidney failure Death, Sudden, Cardiac Diuretics, Potassium Sparing - therapeutic use Glomerular Filtration Rate Humans Hyperkalemia - mortality Hypokalemia - mortality Internal Medicine Kidney diseases Kidney Failure, Chronic - epidemiology Middle Aged Mortality Patient outcomes Potassium - blood Prospective Studies Renal Insufficiency, Chronic - epidemiology Risk factors Sodium Chloride Symporter Inhibitors - therapeutic use United States - epidemiology
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Zusammenfassung:	Abstract Objectives To investigate the association between serum potassium, mortality, and kidney outcomes in the general population and whether potassium-altering medications modify these associations. Patients and Methods We studied 15,539 adults in the Atherosclerosis Risk in Communities Study. Cox proportional hazard regression was used to investigate the association of serum potassium at baseline (1987-1989), evaluated categorically (hypokalemia,
ISSN:	0025-6196 1942-5546
DOI:	10.1016/j.mayocp.2016.05.018