Two cases of serious rhabdomyolysis during linezolid treatment

Linezolid is an oxazolidinone antibiotic with activity against gram-positive organisms, particularly methicillin-resistant Staphylococcus aureus (MRSA). To the best of our knowledge, there are only two case reports on rhabdomyolysis in patients treated with linezolid. Here, we describe two cases of...

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Veröffentlicht in:	Infection 2017-08, Vol.45 (4), p.563-566
Hauptverfasser:	Lechner, Arno M., Past, Eva, Porsche, Ulla, Kern, Jan M., Hoppe, Uta, Pretsch, Ingrid
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Bacterial Agents - toxicity Antibiotics Austria Case Report Case reports Diagnosis, Differential Drug resistance Family Medicine Female General Practice Humans India Infectious Diseases Internal Medicine Linezolid Linezolid - toxicity Male Medical instruments Medicine Medicine & Public Health Methicillin Methicillin-Resistant Staphylococcus aureus - physiology Middle Aged Rhabdomyolysis Rhabdomyolysis - chemically induced Rhabdomyolysis - diagnosis Rhabdomyolysis - drug therapy Sepsis Staphylococcal Infections - drug therapy Staphylococcus aureus Staphylococcus infections Statins Treatment Outcome
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Zusammenfassung:	Linezolid is an oxazolidinone antibiotic with activity against gram-positive organisms, particularly methicillin-resistant Staphylococcus aureus (MRSA). To the best of our knowledge, there are only two case reports on rhabdomyolysis in patients treated with linezolid. Here, we describe two cases of serious rhabdomyolysis: one in a patient with septic community-acquired (CA)-MRSA pneumonia and a second case in a patient with suspected catheter-related blood stream infection.
ISSN:	0300-8126 1439-0973
DOI:	10.1007/s15010-016-0978-8