Lateral thalamic control of nociceptive response after whisker pad injection of varicella zoster virus

Lateral thalamic control of nociceptive response after whisker pad injection of varicella zoster virus

Highlights • VZV injected into the whisker pad induces orofacial pain in rats. • Reduced neuronal activity in the thalamus altered orofacial pain. • GABA signaling in the thalamus gates or inhibits VZV induced facial pain.

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Bibliographische Detailangaben
Veröffentlicht in:Neuroscience 2017-07, Vol.356, p.207-216
Hauptverfasser: Kramer, Phillip, Stinson, Crystal, Umorin, Mikhail, Deng, Mohong, Rao, Mahesh, Bellinger, Larry, Yee, Michael B, Kinchington, Paul R
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Disease Models, Animal
GABA
Herpes Zoster - virology
Herpesvirus 3, Human
Injections - methods
Male
Neuralgia - virology
Neuralgia, Postherpetic - virology
Neurology
orofacial
pain
Rats, Sprague-Dawley
shingles
thalamus
VGAT
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Beschreibung
Zusammenfassung:Highlights • VZV injected into the whisker pad induces orofacial pain in rats. • Reduced neuronal activity in the thalamus altered orofacial pain. • GABA signaling in the thalamus gates or inhibits VZV induced facial pain.
ISSN:0306-4522
1873-7544
DOI:10.1016/j.neuroscience.2017.05.030