Organ-on-a-chip for assessing environmental toxicants

Highlights • Poorly understood xenobiotic toxicants are oversaturating the environment. • Conventional methods are incapable of accurately predicting human physiological responses. • Organ-on-a-chip systems may provide superior models in assessing environmental toxicants. • Human-on-a-chip can serve...

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Veröffentlicht in:	Current opinion in biotechnology 2017-06, Vol.45, p.34-42
Hauptverfasser:	Cho, Soohee, Yoon, Jeong-Yeol
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ecotoxicology - methods Environmental Pollutants - toxicity Humans Internal Medicine Manufactured Materials - toxicity Microfluidics - methods Models, Animal Models, Biological Xenobiotics - isolation & purification
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Highlights • Poorly understood xenobiotic toxicants are oversaturating the environment. • Conventional methods are incapable of accurately predicting human physiological responses. • Organ-on-a-chip systems may provide superior models in assessing environmental toxicants. • Human-on-a-chip can serve as an ultimate platform for evaluating environmental toxicants.
ISSN:	0958-1669 1879-0429
DOI:	10.1016/j.copbio.2016.11.019