Evaluation Expression of Microrna-93 and Integrin Β8 in Different Types of Glioma Tumors

MicroRNAs (miRNAs), are a type of small non-coding RNAs, that induce mRNA degradation or repress translation by binding to the 3′-untranslated region (UTR) of its target mRNA. Some specific miRNAs, e.g. miR-93, have been discovered to be involved in pathological procedures by targeting some oncogene...

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Veröffentlicht in:Asian Pacific journal of cancer prevention : APJCP 2017-03, Vol.18 (3), p.603-608
Hauptverfasser: Malekpour Afshar, Reza, Mollaei, Hamid Reza, Shokrizadeh, Mahdieh, Iranpour, Maryam
Format: Artikel
Sprache:eng
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Zusammenfassung:MicroRNAs (miRNAs), are a type of small non-coding RNAs, that induce mRNA degradation or repress translation by binding to the 3′-untranslated region (UTR) of its target mRNA. Some specific miRNAs, e.g. miR-93, have been discovered to be involved in pathological procedures by targeting some oncogenes or tumor suppressors in glioma. In the present study, real-time RT-PCR data was indicated the expression pattern and prognostic value of miR-93 in patients with types of Glioma.MiR-93 expression was significantly decreased in tumor tissue compared with normal group brain tissues (P
ISSN:1513-7368
2476-762X
DOI:10.22034/APJCP.2017.18.3.603