Metabolic Acidosis and Long-Term Clinical Outcomes in Kidney Transplant Recipients

Metabolic Acidosis and Long-Term Clinical Outcomes in Kidney Transplant Recipients

Metabolic acidosis (MA), indicated by low serum total CO (TCO ) concentration, is a risk factor for mortality and progressive renal dysfunction in CKD. However, the long-term effects of MA on kidney transplant recipients (KTRs) are unclear. We conducted a multicenter retrospective cohort study of 23...

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Veröffentlicht in:Journal of the American Society of Nephrology 2017-06, Vol.28 (6), p.1886-1897
Hauptverfasser: Park, Seokwoo, Kang, Eunjeong, Park, Sehoon, Kim, Yong Chul, Han, Seung Seok, Ha, Jongwon, Kim, Dong Ki, Kim, Sejoong, Park, Su-Kil, Han, Duck Jong, Lim, Chun Soo, Kim, Yon Su, Lee, Jung Pyo, Kim, Young Hoon
Format: Artikel
Sprache:eng
Schlagworte:
Acidosis - epidemiology
Adult
Clinical Research
Cohort Studies
Female
Humans
Kidney Transplantation
Male
Middle Aged
Postoperative Complications - epidemiology
Prevalence
Proportional Hazards Models
Retrospective Studies
Risk Factors
Time Factors
Treatment Outcome
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Zusammenfassung:Metabolic acidosis (MA), indicated by low serum total CO (TCO ) concentration, is a risk factor for mortality and progressive renal dysfunction in CKD. However, the long-term effects of MA on kidney transplant recipients (KTRs) are unclear. We conducted a multicenter retrospective cohort study of 2318 adult KTRs, from January 1, 1997 to March 31, 2015, to evaluate the prevalence of MA and the relationships between TCO concentration and clinical outcomes. The prevalence of low TCO concentration (
ISSN:1046-6673
1533-3450
DOI:10.1681/ASN.2016070793