Modelling the impact of incarceration and prison‐based hepatitis C virus (HCV) treatment on HCV transmission among people who inject drugs in Scotland

Background and Aims People who inject drugs (PWID) experience high incarceration rates, and previous incarceration is associated with elevated hepatitis C virus (HCV) transmission risk. In Scotland, national survey data indicate lower HCV incidence in prison than the community (4.3 versus 7.3 per 10...

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Veröffentlicht in:Addiction (Abingdon, England) England), 2017-07, Vol.112 (7), p.1302-1314
Hauptverfasser: Stone, Jack, Martin, Natasha K., Hickman, Matthew, Hutchinson, Sharon J., Aspinall, Esther, Taylor, Avril, Munro, Alison, Dunleavy, Karen, Peters, Erica, Bramley, Peter, Hayes, Peter C., Goldberg, David J., Vickerman, Peter
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Sprache:eng
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Zusammenfassung:Background and Aims People who inject drugs (PWID) experience high incarceration rates, and previous incarceration is associated with elevated hepatitis C virus (HCV) transmission risk. In Scotland, national survey data indicate lower HCV incidence in prison than the community (4.3 versus 7.3 per 100 person‐years), but a 2.3‐fold elevated transmission risk among recently released (16 weeks) could reduce incidence and prevalence by 45.6% (95% CrI = 38.0–51.3%) and 45.5% (95% CrI = 39.3–51.0%), respectively. Conclusions Incarceration and the elevated transmission risk following prison release can contribute significantly to hepatitis C virus transmission among people who inject drugs. Scaling‐up hepatitis C virus treatment in prison can provide important prevention benefits.
ISSN:0965-2140
1360-0443
DOI:10.1111/add.13783