Highly Tigecycline-Resistant Klebsiella pneumoniae Sequence Type 11 (ST11) and ST147 Isolates from Companion Animals

In this study, we characterized two tigecycline-resistant isolates from dog urine samples. The isolates were genetically unrelated, belonging to sequence type 11 (ST11) and ST147, both classically related to human isolates. To the best of our knowledge, this is the first identification of tigecyclin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Antimicrobial agents and chemotherapy 2017-06, Vol.61 (6)
Hauptverfasser:	Ovejero, Cristina M, Escudero, Jose Antonio, Thomas-Lopez, Daniel, Hoefer, Andreas, Moyano, Gabriel, Montero, Natalia, Martin-Espada, Carmen, Gonzalez-Zorn, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents Anti-Bacterial Agents - pharmacology Bacterial Proteins Bacterial Proteins - genetics Bacterial Proteins - metabolism Drug Resistance, Bacterial - genetics Humans Klebsiella pneumoniae Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - genetics Mechanisms of Action: Physiological Effects Microbial Sensitivity Tests Minocycline Minocycline - analogs & derivatives Minocycline - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	In this study, we characterized two tigecycline-resistant isolates from dog urine samples. The isolates were genetically unrelated, belonging to sequence type 11 (ST11) and ST147, both classically related to human isolates. To the best of our knowledge, this is the first identification of tigecycline-resistant isolates from animals. We unveil here the worrisome circulation among animals of bacterial clones resistant to this last-resort antibiotic.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/aac.02640-16