Differences in Red Blood Cell Indices Do Not Explain Racial Disparity in Hemoglobin A1c in Children with Type 1 Diabetes

Differences in Red Blood Cell Indices Do Not Explain Racial Disparity in Hemoglobin A1c in Children with Type 1 Diabetes

We assessed the association of erythrocyte indices on mean blood glucose-independent racial disparity in hemoglobin A1c (HbA1c) in youth with type 1 diabetes. Blacks still had higher HbA1c after adjustment for mean blood glucose, red blood cell indices, age, and sex. Such differences need to be take...

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Veröffentlicht in:The Journal of pediatrics 2016-09, Vol.176, p.197-199
Hauptverfasser: Hamdan, Mahmoud Adeeb Ahmad, MD, Hempe, James M., PhD, Velasco-Gonzalez, Cruz, PhD, Gomez, Ricardo, MD, Vargas, Alfonso, MD, Chalew, Stuart, MD
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
African Americans
biological variation
Child
Diabetes Mellitus, Type 1 - blood
Erythrocyte Indices
European Continental Ancestry Group
Female
Glycated Hemoglobin A - analysis
Humans
lab interpretation
Male
mean blood glucose
Pediatrics
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Zusammenfassung:We assessed the association of erythrocyte indices on mean blood glucose-independent racial disparity in hemoglobin A1c (HbA1c) in youth with type 1 diabetes. Blacks still had higher HbA1c after adjustment for mean blood glucose, red blood cell indices, age, and sex. Such differences need to be taken into account when interpreting HbA1c in Black patients.
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2016.03.068