Antioxidant and Synergistic Antidiabetic Activities of a Three-Plant Preparation Used in Cameroon Folk Medicine

Introduction. Several plant preparations like a mixture of aqueous extracts of Spilanthes africana; Portulaca oleracea; and Sida rhombifolia are currently utilized in Foumban (West Cameroon) to manage diabetes. The aim of this study is to investigate the antidiabetic property of the aqueous mixture...

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Veröffentlicht in:International scholarly research notices 2017, Vol.2017, p.9501675-7
Hauptverfasser: Moukette, Bruno Moukette, Ama Moor, Vicky Jocelyne, Biapa Nya, Cacral Prosper, Nanfack, Pauline, Nzufo, Francine Tankeu, Kenfack, Marcel Azabji, Ngogang, Jeanne Yonkeu, Pieme, Constant Anatole
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Sprache:eng
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Zusammenfassung:Introduction. Several plant preparations like a mixture of aqueous extracts of Spilanthes africana; Portulaca oleracea; and Sida rhombifolia are currently utilized in Foumban (West Cameroon) to manage diabetes. The aim of this study is to investigate the antidiabetic property of the aqueous mixture of three plant extracts (1 : 1 : 1) on streptozotocin induced diabetes rats. Methods. Diabetes was induced to rats by intraperitoneal (i.p.) injection of streptozotocin (STZ) at a dose of 50 mg/kg b.w. The diabetic rats received different dosages of the mixture of extracts for 21 days and glibenclamide 6.5 mg/kg b.w. as positive control. Results. The results showed that the mixture of extracts significantly (p
ISSN:2356-7872
2356-7872
DOI:10.1155/2017/9501675