Transcriptomic signatures for ovulation in vertebrates

Transcriptomic signatures for ovulation in vertebrates

Highlights • A large set of genes (>10%) differentially expressed during ovulation. • Over 600 genes showed similar increase or decrease in fish, mice, and humans. • Signaling pathways for ovulation are highly conserved in vertebrates. • New candidates for the regulation of ovulation have been id...

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Veröffentlicht in:General and comparative endocrinology 2017-06, Vol.247, p.74-86
Hauptverfasser: Liu, Dong Teng, Brewer, Michael S, Chen, Shixi, Hong, Wanshu, Zhu, Yong
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Down-Regulation - genetics
Endocrinology & Metabolism
Female
Gene Expression Profiling
Gene Knockout Techniques
Humans
Knockout
Mice
Ovulation
Ovulation - genetics
Pgr
Real-Time Polymerase Chain Reaction
Receptors, Progesterone - metabolism
Reproducibility of Results
Sequence Analysis, RNA
TALENs
Transcriptome - genetics
Transcriptomics
Up-Regulation - genetics
Zebrafish
Zebrafish - genetics
Zebrafish - physiology
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Zusammenfassung:Highlights • A large set of genes (>10%) differentially expressed during ovulation. • Over 600 genes showed similar increase or decrease in fish, mice, and humans. • Signaling pathways for ovulation are highly conserved in vertebrates. • New candidates for the regulation of ovulation have been identified.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2017.01.019