Prevalence of Fusobacterium necrophorum in Children Presenting with Pharyngitis
, an obligate anaerobic bacterium, was recently reported to be an important cause of bacterial pharyngitis with a prevalence as high as that of group A (GAS) in adolescents and young adults. Importantly, is the primary causative agent of the life-threatening Lemierre's syndrome, and screening o...
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Veröffentlicht in: | Journal of clinical microbiology 2017-04, Vol.55 (4), p.1147-1153 |
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Sprache: | eng |
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Zusammenfassung: | , an obligate anaerobic bacterium, was recently reported to be an important cause of bacterial pharyngitis with a prevalence as high as that of group A
(GAS) in adolescents and young adults. Importantly,
is the primary causative agent of the life-threatening Lemierre's syndrome, and screening of pharyngeal samples may be warranted for its early detection and prevention. The aim of this study was to determine the prevalences of
and groups A and C/G streptococci as agents of bacterial pharyngitis in children. Pharyngeal samples (
= 300) were collected from pediatric patients presenting to the emergency department with signs and symptoms of pharyngitis. Overall, 10 (3.3%), 79 (26.3%), and 4 (1.3%) patients were PCR positive for
, GAS, and group C/G streptococci, respectively. The prevalence of
was significantly higher in patients between the ages of 14 and 20 years at 13.5% than in patients aged 14 years and younger (1.9%,
< 0.001). All positive patients presented with signs and symptoms similar to GAS pharyngitis. Our data demonstrated a potential role for
as a pathogen of pharyngitis among young adults, but suggests that the prevalence of
is low in preadolescent patients. |
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ISSN: | 0095-1137 1098-660X |
DOI: | 10.1128/JCM.02174-16 |