Influence of camel milk on the hepatitis C virus burden of infected patients

Hepatitis C virus (HCV) infection represents a world health problem and no protective vaccine or effective drug currently exists. For economic reasons, many patients use traditional medicines to control the infection. In Egypt, camel milk is one of the traditional medicines widely consumed by patien...

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Veröffentlicht in:Experimental and therapeutic medicine 2017-04, Vol.13 (4), p.1313-1320
Hauptverfasser: El-Fakharany, Esmail Mohamad, El-Baky, Nawal Abd, Linjawi, Mustafa Hassan, Aljaddawi, Abdullah Abdelhafiz, Saleem, Tahya Hussein, Nassar, Ahmed Yassine, Osman, Ashraf, Redwan, Elrashdy Moustafa
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Sprache:eng
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Zusammenfassung:Hepatitis C virus (HCV) infection represents a world health problem and no protective vaccine or effective drug currently exists. For economic reasons, many patients use traditional medicines to control the infection. In Egypt, camel milk is one of the traditional medicines widely consumed by patients infected with HCV. The present study aimed to evaluate the efficacy of camel milk in the treatment of patients infected with HCV. Whole camel milk from a local farm was administered to patients for 4 months (250 ml/day/patient). Patient sera were collected prior to and following camel milk drinking, and three markers were set-up for sera-evaluation. The three markers indicating the effect of camel milk on HCV infection were: Liver function assays [alanine aminotransferase (ALT) and aspartate aminotransferase (AST)]; a viral load assay; and anti-HCV antibodies profile and isotyping against synthetic HCV epitopes. Camel milk demonstrated the ability to improve general fatigue, health and liver function (ALT and AST levels); ALT was reduced in ~88% of patients and AST was reduced in all patients subsequent to drinking camel milk for four months. The majority of patients responded positively to camel milk treatment; RNA viral load decreased in 13 out of the 17 patients (76.47%) and one patient exhibited undetected viremia following camel milk treatment. The anti-HCV antibodies profile and isotyping were significantly decreased (P
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2017.4159