Effect on Microbial Growth of a New Skin Protectant Formulation

Evaluate the effect of a new investigational skin protectant formulation on the growth of various microorganisms . An laboratory assay with various species of gram-positive bacteria, gram-negative bacteria, and yeast grown on agar plates was used to verify that a new investigational product used for the management of incontinence-associated dermatitis (IAD) does not support microbial growth. The investigational product did not support the growth of all organisms tested for 48 h in these assays. The results demonstrate the barrier properties of this investigational formulation against bacteria and yeast that are relevant to incontinent patients. IAD accompanied by skin damage is difficult to manage with currently available products. A new skin protectant that can be applied as a liquid and polymerizes into a breathable film even in the presence of exudate (as shown previously) has been developed and tested to ensure that it does not support microbial growth. This work verifies that this new product does not support microbial growth using organisms relevant for the intended application.