Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic cardiac glycoside UNBS1450 in acute myeloid leukemia

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Veröffentlicht in:	Leukemia 2017-03, Vol.31 (3), p.755-759
Hauptverfasser:	Cerella, C, Gaigneaux, A, Mazumder, A, Lee, J-Y, Saland, E, Radogna, F, Farge, T, Vergez, F, Récher, C, Sarry, J-E, Kim, K-W, Shin, H Y, Dicato, M, Diederich, M
Format:	Artikel
Sprache:	eng
Schlagworte:	13/2 38/39 45 631/45/612/1243 631/67/1990/283/1897 631/80/82/23 631/92/436/108 64 64/116 692/699/1541/1990/283/1897 82/29 96/31 Acute myelocytic leukemia Apoptosis - drug effects Apoptosis Regulatory Proteins - metabolism bcl-X Protein - metabolism Cancer Research Cardenolides - pharmacology Cardiac Glycosides - pharmacology Care and treatment Cell Line, Tumor Cellular proteins Critical Care Medicine Development and progression Gene expression Genetic aspects Health aspects Hematology Humans Intensive Internal Medicine Letter to the Editor Letters to the editor Leukemia Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - metabolism Medicine Medicine & Public Health Myeloid Cell Leukemia Sequence 1 Protein - metabolism Oncology Patients Protein expression Proteins Proto-Oncogene Proteins c-bcl-2 - metabolism Toxicity U937 Cells
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