Cerebellar Pathology in Early Onset and Late Onset Essential Tremor

Early onset and late onset essential tremor (ET) cases differ in several respects. Whether they differ with respect to cerebellar pathologic changes remains to be determined. We quantified a broad range of postmortem features (Purkinje cell (PC) counts, PC axonal torpedoes and associated axonal chan...

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Veröffentlicht in:Cerebellum (London, England) England), 2017-04, Vol.16 (2), p.473-482
Hauptverfasser: Kuo, Sheng-Han, Wang, Jie, Tate, William J., Pan, Ming-Kai, Kelly, Geoffrey C., Gutierrez, Jesus, Cortes, Etty P., Vonsattel, Jean-Paul G., Louis, Elan D., Faust, Phyllis L.
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Sprache:eng
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Zusammenfassung:Early onset and late onset essential tremor (ET) cases differ in several respects. Whether they differ with respect to cerebellar pathologic changes remains to be determined. We quantified a broad range of postmortem features (Purkinje cell (PC) counts, PC axonal torpedoes and associated axonal changes, heterotopic PCs, and hairy basket ratings) in 30 ET cases with age of tremor onset
ISSN:1473-4222
1473-4230
DOI:10.1007/s12311-016-0826-5