The interplay between neurons and glia in synapse development and plasticity

The interplay between neurons and glia in synapse development and plasticity

Highlights • Proper connectivity of neuronal circuits require the function of glial cells. • Astrocytes and microglia control synapse formation, elimination and plasticity. • Synaptic and circuit plasticity is regulated by astrocytes and microglia. • Neurological disorders may arise through aberrant...

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Veröffentlicht in:Current opinion in neurobiology 2017-02, Vol.42, p.1-8
Hauptverfasser: Stogsdill, Jeff A, Eroglu, Cagla
Format: Artikel
Sprache:eng
Schlagworte:
Brain - growth & development
Brain - pathology
Brain - physiology
Humans
Neuroglia - metabolism
Neurology
Neuronal Plasticity - physiology
Neurons - metabolism
Psychiatry
Synapses - pathology
Synapses - physiology
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Zusammenfassung:Highlights • Proper connectivity of neuronal circuits require the function of glial cells. • Astrocytes and microglia control synapse formation, elimination and plasticity. • Synaptic and circuit plasticity is regulated by astrocytes and microglia. • Neurological disorders may arise through aberrant glia–neuron communication.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2016.09.016