Evaluating surveillance imaging for diffuse large B-cell lymphoma and Hodgkin lymphoma

Up to 50% of patients with Hodgkin lymphoma and diffuse large B-cell lymphoma will relapse, requiring additional therapy. Although surveillance imaging is commonly performed in clinical practice, its ability to identify asymptomatic relapses and improve survival for patients is not well defined. We...

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Veröffentlicht in:Blood 2017-02, Vol.129 (5), p.561-564
Hauptverfasser: Cohen, Jonathon B., Behera, Madhusmita, Thompson, Carrie A., Flowers, Christopher R.
Format: Artikel
Sprache:eng
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Zusammenfassung:Up to 50% of patients with Hodgkin lymphoma and diffuse large B-cell lymphoma will relapse, requiring additional therapy. Although surveillance imaging is commonly performed in clinical practice, its ability to identify asymptomatic relapses and improve survival for patients is not well defined. We evaluated the surveillance imaging role in relapse detection and reviewed its impact on survival for relapsed patients, and found that current imaging approaches do not detect most relapses prior to clinical signs and symptoms or improve survival.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2016-08-685073