Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2

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Bibliographische Detailangaben
Veröffentlicht in:	Leukemia 2016-11, Vol.30 (11), p.2254-2258
Hauptverfasser:	Eisfeld, A-K, Kohlschmidt, J, Mrózek, K, Blachly, J S, Nicolet, D, Kroll, K, Orwick, S, Carroll, A J, Stone, R M, de la Chapelle, A, Byrd, J C, Bloomfield, C D
Format:	Artikel
Sprache:	eng
Schlagworte:	45/23 45/47 45/91 631/208/1405 631/208/2489/1381 631/208/69 631/208/737 631/67/1990/283/1897 692/699/67/68 Acute myeloid leukemia Adult Aged Aged, 80 and over Bone marrow Cancer Research Chromosomes, Human, Pair 11 Clinical trials Critical Care Medicine DNA (Cytosine-5-)-Methyltransferases - genetics Female fms-Like Tyrosine Kinase 3 - genetics Gene expression Gene mutations Genes Health aspects Hematology Histone-Lysine N-Methyltransferase - genetics Humans Intensive Internal Medicine Isocitrate Dehydrogenase - genetics Kinases letter-to-the-editor Letters to the editor Leukemia Leukemia, Myeloid, Acute - genetics Male Medicine Medicine & Public Health Middle Aged Mutation Myeloid-Lymphoid Leukemia Protein - genetics Oncology Patients Remission (Medicine) Splicing Factor U2AF - genetics Survival analysis Trisomy
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