Diabetes mellitus alters the mechanical properties of the native tendon in an experimental rat model

The purpose of this study was to determine the effect of the diabetic phenotype on the mechanical properties of the native patellar tendon and its enthesis. Diabetes was induced via intraperitoneal injection of streptozotocin in Lewis rats. Control (n = 18) and diabetic animals (n = 20) were killed...

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Veröffentlicht in:Journal of orthopaedic research 2011-06, Vol.29 (6), p.880-885
Hauptverfasser: Fox, Alice J. S., Bedi, Asheesh, Deng, Xiang-Hua, Ying, Liang, Harris, Paul E., Warren, Russell F., Rodeo, Scott A.
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Sprache:eng
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Zusammenfassung:The purpose of this study was to determine the effect of the diabetic phenotype on the mechanical properties of the native patellar tendon and its enthesis. Diabetes was induced via intraperitoneal injection of streptozotocin in Lewis rats. Control (n = 18) and diabetic animals (n = 20) were killed at 12 and 19 days for analysis. Statistical comparisons were performed using Student's t‐tests and a two‐tailed Fisher test with significance set at p 
ISSN:0736-0266
1554-527X
DOI:10.1002/jor.21327