A new target for differentiation therapy in AML

Despite major advances in under- standing the genetics and epigenetics of acute myelogenous leukemia, there is still a great need to develop more specific and effective therapies. High throughput approaches involving either genetic approaches or small molecule inhibitor screens are begin- ning to id...

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Veröffentlicht in:Cell research 2017-01, Vol.27 (1), p.9-10
Hauptverfasser: Ma, Peilin, Song, Weihua, Hess, Jay L
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container_title Cell research
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creator Ma, Peilin
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description Despite major advances in under- standing the genetics and epigenetics of acute myelogenous leukemia, there is still a great need to develop more specific and effective therapies. High throughput approaches involving either genetic approaches or small molecule inhibitor screens are begin- ning to identify promising new thera- peutic targets.
doi_str_mv 10.1038/cr.2016.130
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subjects 631/208/2489/68
631/45/607/1168
692/699/67/1059/602
692/699/67/1990/283/1897
AML
Biomedical and Life Sciences
Cell Biology
Genetics
Leukemia
Life Sciences
Research Highlight
分化
小分子
抑制剂
治疗
白血病
表观遗传学
靶点
title A new target for differentiation therapy in AML
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