A new target for differentiation therapy in AML

Despite major advances in under- standing the genetics and epigenetics of acute myelogenous leukemia, there is still a great need to develop more specific and effective therapies. High throughput approaches involving either genetic approaches or small molecule inhibitor screens are begin- ning to id...

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Veröffentlicht in:Cell research 2017-01, Vol.27 (1), p.9-10
Hauptverfasser: Ma, Peilin, Song, Weihua, Hess, Jay L
Format: Artikel
Sprache:eng
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Zusammenfassung:Despite major advances in under- standing the genetics and epigenetics of acute myelogenous leukemia, there is still a great need to develop more specific and effective therapies. High throughput approaches involving either genetic approaches or small molecule inhibitor screens are begin- ning to identify promising new thera- peutic targets.
ISSN:1001-0602
1748-7838
DOI:10.1038/cr.2016.130