Increased cardiovascular risk of treated white coat and masked hypertension in patients with diabetes and chronic kidney disease: the HONEST Study

The prognostic implications of treated white coat hypertension (WCH) and masked hypertension (MH) in patients with diabetes mellitus (DM) or chronic kidney disease (CKD) are not well documented. Using data from the HONEST study (n=21 591), we investigated the relationships between morning home systo...

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Veröffentlicht in:Hypertension research 2017-01, Vol.40 (1), p.87-95
Hauptverfasser: Kushiro, Toshio, Kario, Kazuomi, Saito, Ikuo, Teramukai, Satoshi, Sato, Yuki, Okuda, Yasuyuki, Shimada, Kazuyuki
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Sprache:eng
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Zusammenfassung:The prognostic implications of treated white coat hypertension (WCH) and masked hypertension (MH) in patients with diabetes mellitus (DM) or chronic kidney disease (CKD) are not well documented. Using data from the HONEST study (n=21 591), we investigated the relationships between morning home systolic blood pressure (MHSBP) or clinic systolic blood pressure (CSBP) and cardiovascular (CV) risk in hypertensive patients with and without DM or CKD receiving olmesartan-based antihypertensive therapy. The study included 4426 DM patients and 4346 CKD patients at baseline who had 101 and 87 major CV events, respectively, during the follow-up. Compared with well-controlled non-DM patients (MHSBP
ISSN:0916-9636
1348-4214
DOI:10.1038/hr.2016.87