High Frequency of OXA-253-Producing Acinetobacter baumannii in Different Hospitals in Recife, Brazil

Here, we report the isolation of 31 Acinetobacter baumannii strains producing OXA-253 in a single large Brazilian city. These strains belonged to five different sequence types (STs), including 4 STs not previously associated with bla In all strains, the bla gene was located in a plasmid within a gen...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2017-01, Vol.61 (1)
Hauptverfasser:	de Sá Cavalcanti, Felipe Lira, Mendes-Marques, Carina Lucena, Vasconcelos, Crhisllane Rafaele Dos Santos, de Lima Campos, Túlio, Rezende, Antonio Mauro, Xavier, Danilo Elias, Leal, Nilma Cintra, de-Melo-Neto, Osvaldo Pompilio, de Morais, Marcia Maria Camargo, Leal-Balbino, Tereza Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Acinetobacter baumannii Acinetobacter baumannii - drug effects Acinetobacter baumannii - enzymology Acinetobacter baumannii - genetics Anti-Bacterial Agents Anti-Bacterial Agents - pharmacology beta-Lactamases beta-Lactamases - genetics beta-Lactamases - metabolism Brazil Hospitals Italy Mechanisms of Resistance Microbial Sensitivity Tests Plasmids - genetics
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Zusammenfassung:	Here, we report the isolation of 31 Acinetobacter baumannii strains producing OXA-253 in a single large Brazilian city. These strains belonged to five different sequence types (STs), including 4 STs not previously associated with bla In all strains, the bla gene was located in a plasmid within a genetic environment similar to what was found previously in Brazil and Italy. The reported data emphasize the successful transmission of the bla gene through a large area and the tendency for this resistance determinant to remain in the A. baumannii population.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.01309-16