A breath of fresh air for umbilical cord blood

In this issue of Blood , Aljitawi et al demonstrate for the first time that erythropoietin (EPO) signaling directly inhibits hematopoietic stem and progenitor cell (HSPC) migration and that an acute and transient reduction in peripheral EPO levels, via hyperbaric oxygen (HBO) therapy just before tra...

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Veröffentlicht in:Blood 2016-12, Vol.128 (25), p.2878-2880
1. Verfasser: McKinney-Freeman, Shannon L.
Format: Artikel
Sprache:eng
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Zusammenfassung:In this issue of Blood , Aljitawi et al demonstrate for the first time that erythropoietin (EPO) signaling directly inhibits hematopoietic stem and progenitor cell (HSPC) migration and that an acute and transient reduction in peripheral EPO levels, via hyperbaric oxygen (HBO) therapy just before transplant, is safe and can enhance hematopoietic engraftment in patients undergoing umbilical cord blood transplantation (UCBT). 1
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2016-11-748202