Magnetic Resonance Venous Volume Measurements in Peripheral Artery Disease (From ELIMIT)
Abstract The relationship between the arterial and venous system in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery...
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| Veröffentlicht in: | The American journal of cardiology 2016-11, Vol.118 (9), p.1399-1404 |
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| creator | Kamran, Hassan, MD Nambi, Vijay, MD, PhD Negi, Smita, MD Yang, Eric Y., MD, PhD Chen, Changyi, MD, PhD Virani, Salim S., MD, PhD Kougias, Panagiotis, MD Lumsden, Alan B., MD Morrisett, Joel D., PhD Ballantyne, Christie M., MD Brunner, Gerd, PhD |
| description | Abstract The relationship between the arterial and venous system in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery Disease Trial (ELIMIT) was to determine the association between femoral vein (FV) volumes and measures of peripheral artery disease (PAD). FV wall, lumen, and total volumes were quantified with fast spin-echo (FSE) proton density weighted (PDW) MRI scans in 79 PAD patients over 2-years. Reproducibility was excellent for FV total vessel (intra-class correlation coefficient [ICC] =0.924, confidence interval (CI) 0.910-0.935) and lumen volumes (ICC=0.893, CI 0.873-0.910). Baseline superficial femoral artery (SFA) volumes were directly associated with FV wall (r=0.46, p |
| doi_str_mv | 10.1016/j.amjcard.2016.07.051 |
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The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery Disease Trial (ELIMIT) was to determine the association between femoral vein (FV) volumes and measures of peripheral artery disease (PAD). FV wall, lumen, and total volumes were quantified with fast spin-echo (FSE) proton density weighted (PDW) MRI scans in 79 PAD patients over 2-years. Reproducibility was excellent for FV total vessel (intra-class correlation coefficient [ICC] =0.924, confidence interval (CI) 0.910-0.935) and lumen volumes (ICC=0.893, CI 0.873-0.910). Baseline superficial femoral artery (SFA) volumes were directly associated with FV wall (r=0.46, p<0.0001), lumen (r=0.42, p=0.0001), and total volumes (r=0.46, p<0.0001). The 2-year change in maximum walking time (MWT) was inversely associated with the 24-month change in FV total volume (r=-0.45, p=0.03). In conclusion, FV volumes can be measured reliably with FSE PDW MRI and baseline SFA plaque burden is positively associated with FV volumes, whereas the 2-year change in FV volumes and leg function show an inverse relation.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2016.07.051</identifier><identifier>PMID: 27670795</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Blood Volume ; Body mass index ; Cardiovascular ; Double-Blind Method ; Female ; Femoral Vein - diagnostic imaging ; Humans ; Leg - blood supply ; Magnetic Resonance Imaging - methods ; Male ; Middle Aged ; NMR ; Nuclear magnetic resonance ; Peripheral Arterial Disease - diagnostic imaging ; Quality ; Regression analysis ; Reproducibility of Results ; Risk Factors ; Walk Test</subject><ispartof>The American journal of cardiology, 2016-11, Vol.118 (9), p.1399-1404</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Nov 1, 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c583t-8e8ceaaa57de0f17f6bcce7c9244822679be1a30cce954f29797512a9d9865993</citedby><cites>FETCH-LOGICAL-c583t-8e8ceaaa57de0f17f6bcce7c9244822679be1a30cce954f29797512a9d9865993</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0002914916313212$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27670795$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kamran, Hassan, MD</creatorcontrib><creatorcontrib>Nambi, Vijay, MD, PhD</creatorcontrib><creatorcontrib>Negi, Smita, MD</creatorcontrib><creatorcontrib>Yang, Eric Y., MD, PhD</creatorcontrib><creatorcontrib>Chen, Changyi, MD, PhD</creatorcontrib><creatorcontrib>Virani, Salim S., MD, PhD</creatorcontrib><creatorcontrib>Kougias, Panagiotis, MD</creatorcontrib><creatorcontrib>Lumsden, Alan B., MD</creatorcontrib><creatorcontrib>Morrisett, Joel D., PhD</creatorcontrib><creatorcontrib>Ballantyne, Christie M., MD</creatorcontrib><creatorcontrib>Brunner, Gerd, PhD</creatorcontrib><title>Magnetic Resonance Venous Volume Measurements in Peripheral Artery Disease (From ELIMIT)</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Abstract The relationship between the arterial and venous system in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery Disease Trial (ELIMIT) was to determine the association between femoral vein (FV) volumes and measures of peripheral artery disease (PAD). FV wall, lumen, and total volumes were quantified with fast spin-echo (FSE) proton density weighted (PDW) MRI scans in 79 PAD patients over 2-years. Reproducibility was excellent for FV total vessel (intra-class correlation coefficient [ICC] =0.924, confidence interval (CI) 0.910-0.935) and lumen volumes (ICC=0.893, CI 0.873-0.910). Baseline superficial femoral artery (SFA) volumes were directly associated with FV wall (r=0.46, p<0.0001), lumen (r=0.42, p=0.0001), and total volumes (r=0.46, p<0.0001). The 2-year change in maximum walking time (MWT) was inversely associated with the 24-month change in FV total volume (r=-0.45, p=0.03). In conclusion, FV volumes can be measured reliably with FSE PDW MRI and baseline SFA plaque burden is positively associated with FV volumes, whereas the 2-year change in FV volumes and leg function show an inverse relation.</description><subject>Blood Volume</subject><subject>Body mass index</subject><subject>Cardiovascular</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Femoral Vein - diagnostic imaging</subject><subject>Humans</subject><subject>Leg - blood supply</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Middle Aged</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Peripheral Arterial Disease - diagnostic imaging</subject><subject>Quality</subject><subject>Regression analysis</subject><subject>Reproducibility of Results</subject><subject>Risk Factors</subject><subject>Walk Test</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNksFu1DAQhi0EosvCI4AscSmHBNuJY_vSqiotrLQrEJSKm-V1Jq2XxFnspNK-PY52KdALnKyxv_k9M_8g9JKSnBJavd3kpttYE-qcpTAnIiecPkIzKoXKqKLFYzQjhLBM0VIdoWcxblJIKa-eoiMmKkGE4jP0bWVuPAzO4s8Qe2-8BXwNvh8jvu7bsQO8AhPHAB34IWLn8ScIbnsLwbT4LAwQdvidi4kBfHwZ-g5fLBerxdWb5-hJY9oILw7nHH29vLg6_5AtP75fnJ8tM8tlMWQSpAVjDBc1kIaKplpbC8IqVpaSsUqoNVBTkHSpeNkwJZTglBlVK1lxpYo5Otnrbsd1B7VNZabS9Da4zoSd7o3Tf794d6tv-jvNqVCkEEng-CAQ-h8jxEF3LlpoW-MhjUFTmSBGpJT_g3Keik66c_T6Abrpx-DTJCaqLCouVJUovqds6GMM0NzXTYmebNYbfbBZTzZrInSyOeW9-rPp-6xfvibgdA9AGv2dg6CjdZDMrV0AO-i6d__84uSBgm2dd9a032EH8Xc3OjJN9Jdp16ZVo1VBC0ZZ8ROJiM-l</recordid><startdate>20161101</startdate><enddate>20161101</enddate><creator>Kamran, Hassan, MD</creator><creator>Nambi, Vijay, MD, PhD</creator><creator>Negi, Smita, MD</creator><creator>Yang, Eric Y., MD, PhD</creator><creator>Chen, Changyi, MD, PhD</creator><creator>Virani, Salim S., MD, PhD</creator><creator>Kougias, Panagiotis, MD</creator><creator>Lumsden, Alan B., MD</creator><creator>Morrisett, Joel D., PhD</creator><creator>Ballantyne, Christie M., MD</creator><creator>Brunner, Gerd, PhD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>7QO</scope><scope>5PM</scope></search><sort><creationdate>20161101</creationdate><title>Magnetic Resonance Venous Volume Measurements in Peripheral Artery Disease (From ELIMIT)</title><author>Kamran, Hassan, MD ; Nambi, Vijay, MD, PhD ; Negi, Smita, MD ; Yang, Eric Y., MD, PhD ; Chen, Changyi, MD, PhD ; Virani, Salim S., MD, PhD ; Kougias, Panagiotis, MD ; Lumsden, Alan B., MD ; Morrisett, Joel D., PhD ; Ballantyne, Christie M., MD ; Brunner, Gerd, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c583t-8e8ceaaa57de0f17f6bcce7c9244822679be1a30cce954f29797512a9d9865993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Blood Volume</topic><topic>Body mass index</topic><topic>Cardiovascular</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Femoral Vein - diagnostic imaging</topic><topic>Humans</topic><topic>Leg - blood supply</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Middle Aged</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Peripheral Arterial Disease - diagnostic imaging</topic><topic>Quality</topic><topic>Regression analysis</topic><topic>Reproducibility of Results</topic><topic>Risk Factors</topic><topic>Walk Test</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kamran, Hassan, MD</creatorcontrib><creatorcontrib>Nambi, Vijay, MD, PhD</creatorcontrib><creatorcontrib>Negi, Smita, MD</creatorcontrib><creatorcontrib>Yang, Eric Y., MD, PhD</creatorcontrib><creatorcontrib>Chen, Changyi, MD, PhD</creatorcontrib><creatorcontrib>Virani, Salim S., MD, PhD</creatorcontrib><creatorcontrib>Kougias, Panagiotis, MD</creatorcontrib><creatorcontrib>Lumsden, Alan B., MD</creatorcontrib><creatorcontrib>Morrisett, Joel D., PhD</creatorcontrib><creatorcontrib>Ballantyne, Christie M., MD</creatorcontrib><creatorcontrib>Brunner, Gerd, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest research library</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kamran, Hassan, MD</au><au>Nambi, Vijay, MD, PhD</au><au>Negi, Smita, MD</au><au>Yang, Eric Y., MD, PhD</au><au>Chen, Changyi, MD, PhD</au><au>Virani, Salim S., MD, PhD</au><au>Kougias, Panagiotis, MD</au><au>Lumsden, Alan B., MD</au><au>Morrisett, Joel D., PhD</au><au>Ballantyne, Christie M., MD</au><au>Brunner, Gerd, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetic Resonance Venous Volume Measurements in Peripheral Artery Disease (From ELIMIT)</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>2016-11-01</date><risdate>2016</risdate><volume>118</volume><issue>9</issue><spage>1399</spage><epage>1404</epage><pages>1399-1404</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>Abstract The relationship between the arterial and venous system in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery Disease Trial (ELIMIT) was to determine the association between femoral vein (FV) volumes and measures of peripheral artery disease (PAD). FV wall, lumen, and total volumes were quantified with fast spin-echo (FSE) proton density weighted (PDW) MRI scans in 79 PAD patients over 2-years. Reproducibility was excellent for FV total vessel (intra-class correlation coefficient [ICC] =0.924, confidence interval (CI) 0.910-0.935) and lumen volumes (ICC=0.893, CI 0.873-0.910). Baseline superficial femoral artery (SFA) volumes were directly associated with FV wall (r=0.46, p<0.0001), lumen (r=0.42, p=0.0001), and total volumes (r=0.46, p<0.0001). The 2-year change in maximum walking time (MWT) was inversely associated with the 24-month change in FV total volume (r=-0.45, p=0.03). In conclusion, FV volumes can be measured reliably with FSE PDW MRI and baseline SFA plaque burden is positively associated with FV volumes, whereas the 2-year change in FV volumes and leg function show an inverse relation.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27670795</pmid><doi>10.1016/j.amjcard.2016.07.051</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Blood Volume Body mass index Cardiovascular Double-Blind Method Female Femoral Vein - diagnostic imaging Humans Leg - blood supply Magnetic Resonance Imaging - methods Male Middle Aged NMR Nuclear magnetic resonance Peripheral Arterial Disease - diagnostic imaging Quality Regression analysis Reproducibility of Results Risk Factors Walk Test |
| title | Magnetic Resonance Venous Volume Measurements in Peripheral Artery Disease (From ELIMIT) |
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