Magnetic Resonance Venous Volume Measurements in Peripheral Artery Disease (From ELIMIT)

Magnetic Resonance Venous Volume Measurements in Peripheral Artery Disease (From ELIMIT)

Abstract The relationship between the arterial and venous system in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery...

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Veröffentlicht in:The American journal of cardiology 2016-11, Vol.118 (9), p.1399-1404
Hauptverfasser: Kamran, Hassan, MD, Nambi, Vijay, MD, PhD, Negi, Smita, MD, Yang, Eric Y., MD, PhD, Chen, Changyi, MD, PhD, Virani, Salim S., MD, PhD, Kougias, Panagiotis, MD, Lumsden, Alan B., MD, Morrisett, Joel D., PhD, Ballantyne, Christie M., MD, Brunner, Gerd, PhD
Format: Artikel
Sprache:eng
Schlagworte:
Blood Volume
Body mass index
Cardiovascular
Double-Blind Method
Female
Femoral Vein - diagnostic imaging
Humans
Leg - blood supply
Magnetic Resonance Imaging - methods
Male
Middle Aged
NMR
Nuclear magnetic resonance
Peripheral Arterial Disease - diagnostic imaging
Quality
Regression analysis
Reproducibility of Results
Risk Factors
Walk Test
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Zusammenfassung:Abstract The relationship between the arterial and venous system in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery Disease Trial (ELIMIT) was to determine the association between femoral vein (FV) volumes and measures of peripheral artery disease (PAD). FV wall, lumen, and total volumes were quantified with fast spin-echo (FSE) proton density weighted (PDW) MRI scans in 79 PAD patients over 2-years. Reproducibility was excellent for FV total vessel (intra-class correlation coefficient [ICC] =0.924, confidence interval (CI) 0.910-0.935) and lumen volumes (ICC=0.893, CI 0.873-0.910). Baseline superficial femoral artery (SFA) volumes were directly associated with FV wall (r=0.46, p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2016.07.051