Transplacental Maternal Engraftment and Post-Transplant Graft-versus-Host Disease in Children with Severe Combined Immunodeficiency

Transplacental Maternal Engraftment and Post-Transplant Graft-versus-Host Disease in Children with Severe Combined Immunodeficiency

The presence of transplacental maternal engraftment (TME) varies in pre-transplant SCID patients. This study demonstrates that pre-transplant TME is an independent risk factor for the development of post-transplant acute graft-versus-host disease.

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Veröffentlicht in:Journal of allergy and clinical immunology 2016-06, Vol.139 (2), p.628-633.e10
Hauptverfasser: Wahlstrom, Justin, Patel, Kiran, Eckhert, Erik, Kong, Denice, Horn, Biljana, Cowan, Morton J., Dvorak, Christopher C.
Format: Artikel
Sprache:eng
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Zusammenfassung:The presence of transplacental maternal engraftment (TME) varies in pre-transplant SCID patients. This study demonstrates that pre-transplant TME is an independent risk factor for the development of post-transplant acute graft-versus-host disease.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.04.049