Ethnic and Sex Differences in Adiponectin: From Childhood to Adulthood

Context: Insulin resistance (IR) and type 2 diabetes are increasing, particularly in Hispanic (H) vs non-Hispanic White (NHW) populations. Adiponectin has a known role in IR, and therefore, understanding ethnic and sex-specific behavior of adiponectin across the lifespan is of clinical significance....

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2016-12, Vol.101 (12), p.4808-4815
Hauptverfasser:	Ohman-Hanson, Rebecca A, Cree-Green, Melanie, Kelsey, Megan M, Bessesen, Daniel H, Sharp, Teresa A, Pyle, Laura, Pereira, Rocio I, Nadeau, Kristen J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin - blood Adolescent Adult Child Colorado - ethnology Cross-Sectional Studies European Continental Ancestry Group - ethnology Female Hispanic Americans - statistics & numerical data Human Development - physiology Humans Insulin Resistance - ethnology Male Middle Aged Original Puberty - blood Sex Factors Young Adult
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Zusammenfassung:	Context: Insulin resistance (IR) and type 2 diabetes are increasing, particularly in Hispanic (H) vs non-Hispanic White (NHW) populations. Adiponectin has a known role in IR, and therefore, understanding ethnic and sex-specific behavior of adiponectin across the lifespan is of clinical significance. Objective: To compare ethnic and sex differences in adiponectin, independent of body mass index, across the lifespan and relationship to IR. Design: Cross-sectional. Setting: Primary care, referral center. Patients: A total of 187 NHW and 117 H participants (8–57 y) without diabetes. Life stage: pre-/early puberty (Tanner 1/2), midpubertal (Tanner 3/4), late pubertal (Tanner 5,
ISSN:	0021-972X 1945-7197
DOI:	10.1210/jc.2016-1137