Endometrial gene expression profile of pregnant sows with extreme phenotypes for reproductive efficiency

Prolificacy can directly impact porcine profitability, but large genetic variation and low heritability have been found regarding litter size among porcine breeds. To identify key differences in gene expression associated to swine reproductive efficiency, we performed a transcriptome analysis of sow...

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Veröffentlicht in:	Scientific reports 2015-10, Vol.5 (1), p.14416-14416, Article 14416
Hauptverfasser:	Córdoba, S., Balcells, I., Castelló, A., Ovilo, C., Noguera, J. L., Timoneda, O., Sánchez, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	38/39 38/91 45/90 631/208 631/208/212/2019 Animals Breeding Economics Endometrium Endometrium - metabolism Female Gene expression Gene mapping Gene Ontology Gene Regulatory Networks Genetic Association Studies Genetic diversity Gestation Heritability Hogs Humanities and Social Sciences MicroRNAs - genetics MicroRNAs - metabolism Molecular Sequence Annotation multidisciplinary Neutrophil collagenase Phenotype Pregnancy Quantitative Trait Loci RNA Interference Science Sodium channels Sus scrofa - genetics Sus scrofa - metabolism Transcriptome
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Zusammenfassung:	Prolificacy can directly impact porcine profitability, but large genetic variation and low heritability have been found regarding litter size among porcine breeds. To identify key differences in gene expression associated to swine reproductive efficiency, we performed a transcriptome analysis of sows’ endometrium from an Iberian x Meishan F 2 population at day 30–32 of gestation, classified according to their estimated breeding value (EBV) as high (H, EBV > 0) and low (L, EBV
ISSN:	2045-2322 2045-2322
DOI:	10.1038/srep14416