Safety and Efficacy of Atorvastatin in Human Immunodeficiency Virus-infected Children, Adolescents and Young Adults With Hyperlipidemia

BACKGROUND:Human immunodeficiency virus (HIV)-infected children receiving antiretroviral therapy (ART) have increased prevalence of hyperlipidemia and risk factors for cardiovascular disease. No studies have investigated the efficacy and safety of statins in this population. METHODS:HIV-infected you...

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Veröffentlicht in:	The Pediatric infectious disease journal 2017-01, Vol.36 (1), p.53-60
Hauptverfasser:	Melvin, Ann J, Montepiedra, Grace, Aaron, Lisa, Meyer, William A, Spiegel, Hans M, Borkowsky, William, Abzug, Mark J, Best, Brookie M, Crain, Marilyn J, Borum, Peggy R, Graham, Bobbie, Anthony, Patricia, Shin, Katherine, Siberry, George K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anti-HIV Agents - adverse effects Anti-HIV Agents - therapeutic use Atorvastatin Calcium - adverse effects Atorvastatin Calcium - therapeutic use C-Reactive Protein - analysis Child Female HIV Infections - complications HIV Infections - drug therapy Humans Hyperlipidemias - complications Male Young Adult
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Zusammenfassung:	BACKGROUND:Human immunodeficiency virus (HIV)-infected children receiving antiretroviral therapy (ART) have increased prevalence of hyperlipidemia and risk factors for cardiovascular disease. No studies have investigated the efficacy and safety of statins in this population. METHODS:HIV-infected youth 10 to
ISSN:	0891-3668 1532-0987
DOI:	10.1097/INF.0000000000001352