Expanding Clinical Laboratory Tobacco Product Evaluation Methods to Loose-leaf Tobacco Vaporizers
Highlights • This is the first human laboratory study of a loose-leaf tobacco vaporizer (LLTV). • LLTV use significantly increased plasma nicotine concentration, but not CO. • LLTV use reduced tobacco abstinence symptom severity, but less so than a cigarette. • Both the LLTV and an ECIG were signifi...
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| Veröffentlicht in: | Drug and alcohol dependence 2016-12, Vol.169, p.33-40 |
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| container_title | Drug and alcohol dependence |
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| creator | Lopez, Alexa A Hiler, Marzena Maloney, Sarah Eissenberg, Thomas Breland, Alison |
| description | Highlights • This is the first human laboratory study of a loose-leaf tobacco vaporizer (LLTV). • LLTV use significantly increased plasma nicotine concentration, but not CO. • LLTV use reduced tobacco abstinence symptom severity, but less so than a cigarette. • Both the LLTV and an ECIG were significantly less satisfying than cigarettes. • Laboratory methods can be expanded to “heat-not-burn” products. |
| doi_str_mv | 10.1016/j.drugalcdep.2016.10.005 |
| format | Article |
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All rights reserved.</rights><rights>Copyright Elsevier Science Ltd. Dec 1, 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c562t-1851fedc91be263857ec9f4e92987faeb9bdae288f5da243e375b2783b6d52bf3</citedby><cites>FETCH-LOGICAL-c562t-1851fedc91be263857ec9f4e92987faeb9bdae288f5da243e375b2783b6d52bf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.drugalcdep.2016.10.005$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,780,784,885,3550,27924,27925,30999,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27768968$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lopez, Alexa A</creatorcontrib><creatorcontrib>Hiler, Marzena</creatorcontrib><creatorcontrib>Maloney, Sarah</creatorcontrib><creatorcontrib>Eissenberg, Thomas</creatorcontrib><creatorcontrib>Breland, Alison</creatorcontrib><title>Expanding Clinical Laboratory Tobacco Product Evaluation Methods to Loose-leaf Tobacco Vaporizers</title><title>Drug and alcohol dependence</title><addtitle>Drug Alcohol Depend</addtitle><description>Highlights • This is the first human laboratory study of a loose-leaf tobacco vaporizer (LLTV). • LLTV use significantly increased plasma nicotine concentration, but not CO. • LLTV use reduced tobacco abstinence symptom severity, but less so than a cigarette. • Both the LLTV and an ECIG were significantly less satisfying than cigarettes. • Laboratory methods can be expanded to “heat-not-burn” products.</description><subject>Abstinence</subject><subject>Acute effects</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Brands</subject><subject>Carbon monoxide</subject><subject>Carbon Monoxide - blood</subject><subject>Cigarettes</subject><subject>Electronic cigarette</subject><subject>Electronic Nicotine Delivery Systems</subject><subject>Female</subject><subject>Heat</subject><subject>Heat-not-burn products</subject><subject>Humans</subject><subject>Laboratories</subject><subject>Laboratory methods</subject><subject>Leaves</subject><subject>Loose-leaf tobacco vaporizer</subject><subject>Male</subject><subject>Markets</subject><subject>Middle Aged</subject><subject>Nebulizers and Vaporizers</subject><subject>Nicotine</subject><subject>Nicotine - blood</subject><subject>Plasma nicotine</subject><subject>Psychiatry</subject><subject>Public Health</subject><subject>Severity</subject><subject>Smoking</subject><subject>Smoking - blood</subject><subject>Substance Withdrawal Syndrome - blood</subject><subject>Symptoms</subject><subject>Tobacco</subject><subject>Tobacco Products</subject><subject>Tobacco Use Disorder - blood</subject><subject>Vaping - blood</subject><subject>Vaporizers</subject><subject>Young Adult</subject><issn>0376-8716</issn><issn>1879-0046</issn><issn>1879-0046</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqNUsuO0zAUtRCIKYVfQJHYsEnxI_FjMxJU5SEVgcTA1nLsm45LGhc7qShfj6OWDswKbyzde-65Pj4HoYLgBcGEv9ouXBw3prMO9guaK7m8wLh-gGZEClViXPGHaIaZ4KUUhF-hJyltcT5c4cfoigrBpeJyhszq5970zvebYtn53lvTFWvThGiGEI_FTWiMtaH4HIMb7VCsDqYbzeBDX3yE4Ta4VAyhWIeQoOzAtJeBb2Yfov8FMT1Fj1rTJXh2vufo69vVzfJ9uf707sPy9bq0NadDSWRNWnBWkQYoZ7IWYFVbgaJKitZAoxpngErZ1s7QigETdUOFZA13NW1aNkfXJ9792OwyEfRDNJ3eR78z8aiD8frfTu9v9SYcdE0qLDLjHL08E8TwY4Q06J1PFrrO9BDGpIlkdU0ZxyRDX9yDbsMY-yxPE0WxqLDkMqPkCWVjSClCe3kMwXryUW_1nY968nHqZB_z6PO_xVwG_xiXAW9OAMhfevAQdbIeegvOR7CDdsH_z5breyT2nIHvcIR0p0knqrH-MuVpihPhDCsmGfsNyWXK6A</recordid><startdate>20161201</startdate><enddate>20161201</enddate><creator>Lopez, Alexa A</creator><creator>Hiler, Marzena</creator><creator>Maloney, Sarah</creator><creator>Eissenberg, Thomas</creator><creator>Breland, Alison</creator><general>Elsevier B.V</general><general>Elsevier Science Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20161201</creationdate><title>Expanding Clinical Laboratory Tobacco Product Evaluation Methods to Loose-leaf Tobacco Vaporizers</title><author>Lopez, Alexa A ; 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| ispartof | Drug and alcohol dependence, 2016-12, Vol.169, p.33-40 |
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| source | MEDLINE; Applied Social Sciences Index & Abstracts (ASSIA); Access via ScienceDirect (Elsevier) |
| subjects | Abstinence Acute effects Adolescent Adult Brands Carbon monoxide Carbon Monoxide - blood Cigarettes Electronic cigarette Electronic Nicotine Delivery Systems Female Heat Heat-not-burn products Humans Laboratories Laboratory methods Leaves Loose-leaf tobacco vaporizer Male Markets Middle Aged Nebulizers and Vaporizers Nicotine Nicotine - blood Plasma nicotine Psychiatry Public Health Severity Smoking Smoking - blood Substance Withdrawal Syndrome - blood Symptoms Tobacco Tobacco Products Tobacco Use Disorder - blood Vaping - blood Vaporizers Young Adult |
| title | Expanding Clinical Laboratory Tobacco Product Evaluation Methods to Loose-leaf Tobacco Vaporizers |
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