Dysbiosis of fecal microbiota and high frequency of Citrobacter, Klebsiella spp., and Actinomycetes in patients with irritable bowel syndrome and gastroenteritis

This study was aimed to characterize putative differences of fecal microbiota between irritable bowel syndrome (IBS) and gastroenteritis patients and healthy controls. New evidence proposed that gut microbiota has a deep effect on the balance between health and disease. The presence of , spp., Enterobacteriacea and Staphylococci were detected in the samples using selective and specific culture media. Microscopic examination of the samples was done to detect Actinomycetes, yeasts, Bifidobacteria, spp , as well as white blood cells, red blood cells, mucus and epithelial cells. Results of this study showed relatively higher frequency of spp., , and n the IBS patients. Elevated levels of WBC, RBC secretion, and increased amounts of , and spp. were characterized in the patients with gastroenteritis compared with the control group. Depletion of gram positive cocci and gram negative bacilli also suggested dysbiosis of intestinal microbiota in these patients.