Why NAD+ Declines during Aging: It’s Destroyed

Why NAD+ Declines during Aging: It’s Destroyed

NAD+ is required not only for life but for a long life. In this issue, Camacho-Pereira et al. (2016) implicate CD38 in the decline of NAD+ during aging, with implications for combating age-related diseases. NAD+ is required not only for life but for a long life. In this issue, Camacho-Pereira et al....

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Veröffentlicht in:Cell metabolism 2016-06, Vol.23 (6), p.965-966
Hauptverfasser: Schultz, Michael B., Sinclair, David A.
Format: Artikel
Sprache:eng
Schlagworte:
ADP-ribosyl Cyclase 1 - metabolism
Aging - metabolism
Animals
Mice
Mitochondria - metabolism
Models, Biological
NAD - metabolism
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Zusammenfassung:NAD+ is required not only for life but for a long life. In this issue, Camacho-Pereira et al. (2016) implicate CD38 in the decline of NAD+ during aging, with implications for combating age-related diseases. NAD+ is required not only for life but for a long life. In this issue, Camacho-Pereira et al. implicate CD38 in the decline of NAD+ during aging, with implications for combating age-related diseases.
ISSN:1550-4131
1932-7420
DOI:10.1016/j.cmet.2016.05.022