Antiretroviral Failure Despite High Levels of Adherence : Discordant Adherence-Response Relationship in Botswana

Antiretroviral Failure Despite High Levels of Adherence : Discordant Adherence-Response Relationship in Botswana

Although adherence to antiretroviral therapy may be higher in sub-Saharan Africa, knowledge regarding the magnitude of adherence needed to maintain virological suppression in this setting is limited. A case-control study among HIV-infected individuals initiating highly active antiretroviral therapy...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of acquired immune deficiency syndromes (1999) 2008-09, Vol.49 (1), p.107-110
Hauptverfasser: BISSON, Gregory P, ROWH, Adam, WEINSTEIN, Rachel, GAOLATHE, Tendani, FRANK, Ian, GROSS, Robert
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
AIDS/HIV
Antiretroviral drugs
Antiretroviral Therapy, Highly Active
Biological and medical sciences
Botswana
Case-Control Studies
Drug therapy
Failure
Female
Fundamental and applied biological sciences. Psychology
HIV
HIV Infections - drug therapy
HIV Infections - virology
HIV-1 - isolation & purification
Human immunodeficiency virus
Human immunodeficiency virus 1
Human viral diseases
Humans
Infectious diseases
Male
Medical sciences
Microbiology
Miscellaneous
Patient Compliance
Studies
Treatment Failure
Viral diseases
Viral Load
Virology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Although adherence to antiretroviral therapy may be higher in sub-Saharan Africa, knowledge regarding the magnitude of adherence needed to maintain virological suppression in this setting is limited. A case-control study among HIV-infected individuals initiating highly active antiretroviral therapy (HAART) in Gaborone, Botswana, was performed. Cases were randomly selected from subjects on HAART > or =6 months with plasma HIV-1 RNA levels (viral loads) >1000 copies/mL. Controls were randomly selected from subjects on HAART > or =6 months with all viral loads
ISSN:1525-4135
1944-7884
DOI:10.1097/QAI.0b013e3181820141