GC–MS Analysis of Bio-active Molecules Derived from Paracoccus pantotrophus FMR19 and the Antimicrobial Activity Against Bacterial Pathogens and MDROs
The present investigation is focused on the study of chemical composition of a bioactive compound derived from a rumen isolate Paracoccus pantotrophus FMR19 using GC–MS and to find out the antibacterial activity of the extracted crude bioactive compounds against multidrug resistant organisms (MDROs)...
Gespeichert in:
Veröffentlicht in: | Indian journal of microbiology 2016-12, Vol.56 (4), p.426-432 |
---|---|
Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | The present investigation is focused on the study of chemical composition of a bioactive compound derived from a rumen isolate
Paracoccus pantotrophus
FMR19 using GC–MS and to find out the antibacterial activity of the extracted crude bioactive compounds against multidrug resistant organisms (MDROs) and other clinical pathogens. GC–MS analysis revealed that
P. pantotrophus
FMR19 produced eight major compounds that have been reported to exhibit antimicrobial property. The main components identified from hexane fraction are long chain alkanes, fatty alcohols, fatty acid methyl ester and aromatic hydrocarbons. These molecules are not only active against clinical pathogens such as
Salmonella
sp. and
Proteus
sp. and also effective against MDROs such as Metallo β lactamase and Pan drug resistant bacterial strains and Methicillin resistant
Staphylococcus aureus
. |
---|---|
ISSN: | 0046-8991 0973-7715 |
DOI: | 10.1007/s12088-016-0609-1 |