Impact of Age on Stent Strut Coverage and Neointimal Remodeling as Assessed by Optical Coherence Tomography

While older age associates with adverse percutaneous coronary intervention (PCI) outcomes, detailed information relating age to stent strut coverage and neointimal characteristics is lacking. One hundred nineteen patients with 123 sirolimus-eluting stents (SESs) were divided into 3 groups: group A (...

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Veröffentlicht in:	Medicine (Baltimore) 2015-12, Vol.94 (50), p.e2246-e2246
Hauptverfasser:	Han, Zhigang, Feng, Linxing, Du, Hongwei, Sun, Zhao, Hu, Sining, Dai, Jiannan, Sun, Meng, Xing, Lei, Hou, Jingbo, Zhang, Shaosong, Yu, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aged Coronary Artery Disease - complications Coronary Artery Disease - diagnosis Coronary Artery Disease - therapy Drug-Eluting Stents Female Humans Immunosuppressive Agents Male Middle Aged Neointima - diagnosis Neointima - etiology Observational Study Percutaneous Coronary Intervention Retrospective Studies Sirolimus Tomography, Optical Coherence Treatment Outcome Vascular Remodeling - physiology
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Zusammenfassung:	While older age associates with adverse percutaneous coronary intervention (PCI) outcomes, detailed information relating age to stent strut coverage and neointimal characteristics is lacking. One hundred nineteen patients with 123 sirolimus-eluting stents (SESs) were divided into 3 groups: group A (≤55 years), group B (56-65 years), and group C (>65 years). At 6 and 12 months of follow-up, optical coherence tomography was performed to assess strut coverage and neointimal remodeling. At 6 months, the proportion of uncovered struts increased with age: 6.1% in group A versus 7.3% in group B versus 11.7% in group C (P
ISSN:	0025-7974 1536-5964
DOI:	10.1097/MD.0000000000002246