An efficient power harvesting mobile phone-based electrochemical biosensor for point-of-care health monitoring

•Device plugs into audio port of mobiles transforming them into molecular sensors.•Can efficiently harvest its power (79% efficiency) from mobile phones.•Measurements match well when compared to data from a benchtop potentiostat.•Platform is able to detect SLPI in the relevant biological range for cystic fibrosis. Cellular phone penetration has grown continually over the past two decades with the number of connected devices rapidly approaching the total world population. Leveraging the worldwide ubiquity and connectivity of these devices, we developed a mobile phone-based electrochemical biosensor platform for point-of-care (POC) diagnostics and wellness tracking. The platform consists of an inexpensive electronic module (