Externally Applied Static Magnetic Field Enhances Cardiac Retention and Functional Benefit of Magnetically Iron‐Labeled Adipose‐Derived Stem Cells in Infarcted Hearts

Although adipose‐derived stem cells (ASCs) hold the promise of effective therapy for myocardial infarction, low cardiac retention of implanted ASCs has hindered their therapeutic efficiency. We investigated whether an externally applied static magnetic field (SMF) enhances cardiac localization of &q...

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Veröffentlicht in:	Stem cells translational medicine 2016-10, Vol.5 (10), p.1380-1393
Hauptverfasser:	Wang, Jian, Xiang, Bo, Deng, Jixian, Lin, Hung-Yu, Zheng, Dayang, Freed, Darren H., Arora, Rakesh C., Tian, Ganghong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - cytology Adipose-derived stem cells Administrative support Angiogenesis Animals Apoptosis Cardiac function Cardiomyocytes Cell culture Cell Differentiation Cell Movement Cell retention Cytokines Data analysis Deoxyribonucleic acid Disease Models, Animal DNA Drug dosages Endothelial cells FDA approval Female Ferric Compounds - pharmacology Flow Cytometry Heart Iron oxides Ischemia Localization Lungs Magnetic Fields Male Metal Nanoparticles Muscle contraction Myocardial Infarction Nanoparticles Paracrine signalling Pilot Projects Rats Rats, Transgenic Retention Science Static magnetic field Stem Cell Transplantation - methods Stem Cells Studies Superparamagnetic iron oxide Tissue Engineering and Regenerative Medicine Vascularization
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