The Blood and Marrow Transplant Clinical Trials Network: An Effective Infrastructure for Addressing Important Issues in Hematopoietic Cell Transplantation

Highlights • The Blood and Marrow Transplant Clinical Trials Network was established in 2001 to conduct multicenter trials addressing important blood and marrow transplantation issues • It has opened 37 trials and published 57 papers addressing diverse issues in malignant and nonmalignant disorders. • The scientific agenda is developed with broad input from the blood and marrow transplantation community • Participation is wide, with >120 centers enrolling >8000 patients over the network's history • Use of the Center for International Blood and Marrow Transplant Research large observational database for trial planning contributes to success