Hip structure analysis by DXA of teriparatide treatment: A 24-month follow-up clinical study

Abstract Objective The objective of this study was to perform a hip structure analysis (HSA) of teriparatide (TPTD) treatment in women with postmenopausal osteoporosis. Methods The study included 96 patients with postmenopausal osteoporosis and received 20 μg TPTD daily. HSA was performed by dual-en...

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Veröffentlicht in:Journal of orthopaedics 2016-12, Vol.13 (4), p.414-418
Hauptverfasser: Mochizuki, Takeshi, Yano, Koichiro, Ikari, Katsunori, Kawakami, Kosei, Hiroshima, Ryo, Koenuma, Naoko, Ishibashi, Mina, Shirahata, Toshikatsu
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Sprache:eng
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Zusammenfassung:Abstract Objective The objective of this study was to perform a hip structure analysis (HSA) of teriparatide (TPTD) treatment in women with postmenopausal osteoporosis. Methods The study included 96 patients with postmenopausal osteoporosis and received 20 μg TPTD daily. HSA was performed by dual-energy X-ray absorptiometry. Results The percent changes from baseline for the cross-sectional moment of inertia, section modulus, buckling ratio, and femoral strength index based on HSA results were 9.8% ( p < 0.01), 10.7%, 3.3%, and 14.9% ( p < 0.01), respectively, at 24 months. Conclusion Based on the HSA results obtained with DXA, TPTD was effective for hip structures.
ISSN:0972-978X
0972-978X
DOI:10.1016/j.jor.2016.09.001