Generation of Functional Cardiomyocytes from the Synoviocytes of Patients with Rheumatoid Arthritis via Induced Pluripotent Stem Cells

Cardiovascular disease is a leading cause of morbidity in rheumatoid arthritis (RA) patients. This study aimed to generate and characterise cardiomyocytes from induced pluripotent stem cells (iPSCs) of RA patients. Fibroblast-like synoviocytes (FLSs) from patients with RA and osteoarthritis (OA) wer...

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Veröffentlicht in:	Scientific reports 2016-09, Vol.6 (1), p.32669-32669, Article 32669
Hauptverfasser:	Lee, Jaecheol, Jung, Seung Min, Ebert, Antje D., Wu, Haodi, Diecke, Sebastian, Kim, Youngkyun, Yi, Hyoju, Park, Sung-Hwan, Ju, Ji Hyeon
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/2171 692/699/1670/498 Antibodies Arthritis, Rheumatoid - pathology Autoimmune diseases Calcium Calcium (intracellular) Calcium signalling Cardiomyocytes Cardiovascular diseases Cell Differentiation Heart Heart diseases Humanities and Social Sciences Humans Immunofluorescence Induced Pluripotent Stem Cells - pathology Intracellular signalling Morbidity multidisciplinary Muscle contraction Myocytes, Cardiac - pathology Osteoarthritis Pluripotency Polymerase chain reaction Reverse transcription Rheumatoid arthritis Science Stem cells Synoviocytes Synoviocytes - pathology
Online-Zugang:	Volltext
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