Prevalence and risk factors for prolonged QT interval and QT dispersion in patients with type 2 diabetes

Aims Prolonged QT interval is associated with cardiac arrhythmias and sudden death. The present study determined the prevalence of prolonged QT interval and QT dispersion and defined their clinical and metabolic predictors in patients with type 2 diabetes. Methods Cross-sectional study included 501...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Acta diabetologica 2016-10, Vol.53 (5), p.737-744
Hauptverfasser: Ninkovic, Vladan M., Ninkovic, Srdjan M., Miloradovic, Vanja, Stanojevic, Dejan, Babic, Marijana, Giga, Vojislav, Dobric, Milan, Trenell, Michael I., Lalic, Nebojsa, Seferovic, Petar M., Jakovljevic, Djordje G.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Aims Prolonged QT interval is associated with cardiac arrhythmias and sudden death. The present study determined the prevalence of prolonged QT interval and QT dispersion and defined their clinical and metabolic predictors in patients with type 2 diabetes. Methods Cross-sectional study included 501 patients with type 2 diabetes. A standard 12-lead electrocardiogram was recorded. QT corrected for heart rate (QTc) >440 ms and QT dispersion (QTd) >80 ms were considered abnormally prolonged. QTc ≥ 500 ms was considered a high-risk QTc prolongation. Demographic, clinical and laboratory data were collected. Independent risk factors for prolonged QTc and QTd were assessed using logistic regression analysis. Results Prevalence of QTc > 440 ms and QTd > 80 ms were 44.1 and 3.6 %, respectively. Prevalence of high-risk QTc (≥500 ms) was 2 % only. Independent risk factors for QTc prolongation >440 ms were mean blood glucose ( β  = 2.192, p  
ISSN:0940-5429
1432-5233
DOI:10.1007/s00592-016-0864-y