Necrotising enterocolitis and mortality in preterm infants after introduction of probiotics: a quasi-experimental study

Evidence on the clinical effectiveness of probiotics in the prevention of necrotising enterocolitis (NEC) in preterm infants is conflicting and cohort studies lacked adjustment for time trend and feeding type. This study investigated the association between the introduction of routine probiotics (La...

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Veröffentlicht in:	Scientific reports 2016-08, Vol.6 (1), p.31643-31643, Article 31643
Hauptverfasser:	Samuels, Noor, van de Graaf, Rob, Been, Jasper V., de Jonge, Rogier C. J., Hanff, Lidwien M., Wijnen, René M. H., Kornelisse, René F., Reiss, Irwin K. M., Vermeulen, Marijn J.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/3187 692/700/1720/3189 Bifidobacterium bifidum Enterocolitis, Necrotizing - mortality Enterocolitis, Necrotizing - therapy Female Humanities and Social Sciences Humans Infant, Newborn Infant, Premature Lactobacillus acidophilus Male multidisciplinary Probiotics - administration & dosage Science
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Zusammenfassung:	Evidence on the clinical effectiveness of probiotics in the prevention of necrotising enterocolitis (NEC) in preterm infants is conflicting and cohort studies lacked adjustment for time trend and feeding type. This study investigated the association between the introduction of routine probiotics (Lactobacillus acidophilus and Bifidobacterium bifidum; Infloran ® ) on the primary outcome ‘NEC or death’. Preterm infants (gestational age
ISSN:	2045-2322 2045-2322
DOI:	10.1038/srep31643